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16 issue of the British Medical Journal, Padwal's team found that long-term users of weight-loss drugs such as orlistat (Xenical), sibutramine (Meridia) and rimonabant experienced only modest weight loss -- less than 11 pounds, which was less than 5 percent of their total body weight. Those trials compared taking rimonabant (20 milligrams a day) against a placebo. 25 percent increase in percent atheroma volume (PAV) in those taking rimonabant, compared to 0. Rimonabant is not yet accustomed for use in the United States, area it is accepted as Zimulti. Rimonabant, brand named Acomplia, is an anti-obesity drug that may help treat addiction, the team noted.
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